Gene description for CD9
Gene name CD9 molecule
Gene symbol CD9
Other names/aliases BTCC-1
DRAP-27
MIC3
MRP-1
TSPAN-29
TSPAN29
Species Homo sapiens
 Experiment description of studies that identified CD9 in Lung cancer cells

1
Experiment ID610
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLung cancer cells
Sample nameHOP-62
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

2
Experiment ID612
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLung cancer cells
Sample nameNCI-H226
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

3
Experiment ID614
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLung cancer cells
Sample nameNCI-H322M
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

4
Experiment ID615
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLung cancer cells
Sample nameNCI-H460
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

5
Experiment ID888
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 24946052   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment
AuthorsChoi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J.
Journal name Proteomics
Publication year2014
SampleLung cancer cells
Sample namePC9
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation densityNot provided
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140109: EV-METRIC:25%

6
Experiment ID892
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 24946052   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment
AuthorsChoi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J.
Journal name Proteomics
Publication year2014
SampleLung cancer cells
Sample namePC9 - gefitinib-resistant
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation densityNot provided
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140109: EV-METRIC:25%

7
Experiment ID1359
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Flow cytometry
EV-TRACK -

8
Experiment ID1360
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Flow cytometry
EV-TRACK -

9
Experiment ID1361
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549 - 4K Pellet
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID1362
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549 - 10K pellet
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID1363
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549 - 100K pellet
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID1364
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

13
Experiment ID1365
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

14
Experiment ID1535
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33589572   
OrganismHomo sapiens
Experiment descriptionExosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis
AuthorsLv X, Lian Y, Liu Z, Xiao J, Zhang D, Yin X.
Journal name Aging
Publication year2021
SampleLung cancer cells
Sample nameHCC827
Isolation/purification methodsCentrifugation
ExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

15
Experiment ID1536
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33589572   
OrganismHomo sapiens
Experiment descriptionExosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis
AuthorsLv X, Lian Y, Liu Z, Xiao J, Zhang D, Yin X.
Journal name Aging
Publication year2021
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsCentrifugation
ExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

16
Experiment ID1827
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36494333   
OrganismHomo sapiens
Experiment descriptionCancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis
AuthorsChang RM, Fu Y, Zeng J, Zhu XY, Gao Y.
Journal name Cell Death Dis
Publication year2022
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsCentrifugation
Filtration
ExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

17
Experiment ID1828
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36494333   
OrganismHomo sapiens
Experiment descriptionCancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis
AuthorsChang RM, Fu Y, Zeng J, Zhu XY, Gao Y.
Journal name Cell Death Dis
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsCentrifugation
Filtration
ExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

18
Experiment ID2104
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

19
Experiment ID2105
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

20
Experiment ID2106
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

21
Experiment ID2107
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

22
Experiment ID2108
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

23
Experiment ID2109
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

24
Experiment ID2112
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

25
Experiment ID2113
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

26
Experiment ID2114
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1299
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

27
Experiment ID2118
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

28
Experiment ID2119
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

29
Experiment ID2120
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

30
Experiment ID2121
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

31
Experiment ID2122
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

32
Experiment ID2123
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

33
Experiment ID2124
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

34
Experiment ID2125
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

35
Experiment ID2126
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36482876   
OrganismHomo sapiens
Experiment descriptionSuppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels
AuthorsChen X, Li J, Zhang R, Zhang Y, Wang X, Leung EL, Ma L, Wong VKW, Liu L, Neher E, Yu H.
Journal name J Extracell Vesicles
Publication year2022
SampleLung cancer cells
Sample nameH1975
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

36
Experiment ID3332
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SampleLung cancer cells
Sample nameCalu-3
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

37
Experiment ID1359
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Flow cytometry
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Flow cytometry
EV-TRACK -

38
Experiment ID1360
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Flow cytometry
PubMed ID 32132711   
OrganismHomo sapiens
Experiment descriptionDecoy exosomes provide protection against bacterial toxins
AuthorsKeller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K.
Journal name Nature
Publication year2020
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Flow cytometry
EV-TRACK -

39
Experiment ID3395
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Flow cytometry
PubMed ID 31792209   
OrganismHomo sapiens
Experiment descriptionEliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
AuthorsXie X, Nie H, Zhou Y, Lian S, Mei H, Lu Y, Dong H, Li F, Li T, Li B, Wang J, Lin M, Wang C, Shao J, Gao Y, Chen J, Xie F, Jia L.
Journal name Nat Commun
Publication year2019
SampleLung cancer cells
Sample nameA549
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFlow cytometry
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